The University of Chicago Medicine (UCM) has created several clinical pathways to support care of COVID19 patients.  UCM is pleased to disseminate this valuable information and HDSI will update this page with new pathways or as pathways are modified.

What are Clinical Pathways?

Kinsman and colleagues (BMC Medicine. 2010, 8:31) describe clinical pathways as:

  • structured multidisciplinary plans of care used to translate evidence into local structures
  • detailing care in an algorithm with criteria-based progression (that is, steps to take if designated criteria are met)
  • which aims to standardize care for a specific clinical problem in a specific population

Clinical pathways integrate evidence-based guidelines with local key stakeholder expertise to promote high value care. They provide a road map for “typical” care, represent the standard of care at UCM and are a foundational approach used in our clinical high reliability program. Implementation of pathways is supported by informatics solutions that promote ease of practice and the adoption of evidence-based interventions that strengthen patient outcomes. Clinical pathways are not meant to replace clinical judgement and patients should be managed based on their unique needs.

See the University of Chicago Medicine’s updated pathways using the AgileMD software or download the PDFs below (the PDFs will be updated every Friday).

COVID-19: Adult Ambulatory Clinics

Printed 11/04/2020

COVID-19: Adult ED

Printed 11/19/2020

COVID-19: Adult Inpatient

Printed 11/30/2020

COVID-19: Adult Inpatient Treatment

Printed 11/23/2020

COVID-19: Adult Respiratory Failure and Cardiac Arrest

Printed 4/16/2020 7:31 PM

COVID-19: Pre-Procedure/Surgery

Printed 11/21/2020

COVID-19: Pre-Procedure/Surgery/ Direct Admit

Printed 11/30/2020

COVID-19: Exposed Inpatient

Printed 7/14/2020 9:54 AM

COVID-19: Adult ED Transfer Process to Comer Inpatient (non-ICU)

Printed 11/10/2020

COVID-19: Inpatient Clearing

Printed 4/29/2020 10:36 AM

COVID-19: Outside Hospital Transfer

Printed 11/30/2020

COVID-19: Pediatric Inpatient

Printed 11/30/2020

COVID-19: Pediatric Ambulatory Clinics

Printed 11/30/2020

COVID-19: Pediatric ED

Printed 11/30/2020

COVID-19: Pediatric Respiratory Failure and/or Cardiac Arrest Outside the ICU

Printed 4/15/2020 4:19 PM

COVID-19: Labor and Delivery

Printed 11/30/2020

COVID-19: Curbside Clinic- Telemedicine

Printed 11/30/2020

Clinical High Reliability

Our system-wide approach for translating evidence into everyday practice by empowering provider decision making at the point of care.


  • Provide perfect care for every patient at the highest value
  • Eliminate unwarranted clinical variation
  • Demonstrate success in priority clinical outcomes (including those that are publically reported)

Other clinical pathways available at UChicago Medicine:

Adult ED:

  • Acute Decompensated Heart Failure
  • Admissions and Consults
  • Adult Trauma Activation Criteria
  • Asthma and COPD
  • Atrial Fibrillation and Flutter
  • Back Pain
  • Chest Pain & Acute Coronary Syndromes (ACS)
  • Dental Pain
  • Febrile Neutropenia (Solid Tumor)
  • Headache
  • Hip Fracture
  • Malignant Bowel Obstruction
  • Pneumonia
  • Pulmonary Embolism
  • Sexual Wellness Clinic Flow
  • Sickle Cell Crisis
  • Social Work, Case Managers, Patient Advocates

Adult Inpatient:

  • Acute Decompensated Heart Failure
  • Adult Sickle Cell Disease – Inpatient Pain Management
  • Atrial Fibrillation and Flutter
  • Chest Pain & Acute Coronary Syndromes (ACS)
  • Malignant Bowel Obstruction
  • Pulmonary Embolism (new admission for PE)
  • Pulmonary Embolism (previously admitted patient with a new PE)


  • Congenital Cytomegalovirus Infection
  • ED Community Acquired Pneumonia
  • ED Croup
  • ED Sepsis
  • Inpatient Community Acquired Pneumonia